Biostimulation in Karlsruhe
Natural collagen production for long-lasting results
Medically reviewed by the Derma Luma medical team · Last updated: October 2026
How Does Biostimulation Work?
Biostimulators like Sculptra® and HArmonyCa stimulate your body's own collagen production. Unlike fillers that provide immediate volume, biostimulators build new collagen over months. The result is natural, long-lasting tightening and rejuvenation from within.
Treatment Areas
Applications
The classic among biostimulators. Poly-L-lactic acid stimulates collagen production over months. Ideal for face and body. Result: Gradual tightening over 3-6 months, lasts 2+ years.
Combines immediate volume (hyaluronic acid) with long-term collagen stimulation (CaHA). Ideal for quick and lasting results. Result: Immediate + gradual improvement, lasts 18+ months.
Suitability
Who is this treatment suitable for?
✓ Suitable for
- •Sagging skin on face and body
- •Desire for natural rejuvenation
- •Long-lasting results desired
- •No overfilled look wanted
- •Patients 40+
✗ Less suitable for
- •Young patients with good skin quality
- •Desire for immediate, significant volume
- •Active skin conditions
- •Pregnancy and breastfeeding
Process
How the treatment works
1
Assessment of skin quality and goals
2
Selection of optimal biostimulator
3
Precise injections (30-45 min.)
4
Distribution of product in tissue through massage
Investment
Prices & Costs
Sculptra® (1 vial)from €699
HArmonyCa™ (2 syringes)from €999
Safety
Risks & Safety
✓FDA/CE-approved products
✓Biocompatible, biodegradable ingredients
✓Decades of clinical experience
✓Natural results
Durability & Aftercare
Sculptra results last 2-3 years, HArmonyCa approximately 18-24 months. The newly formed collagen partially remains even after the product breaks down.
FAQ
Frequently Asked Questions
Fillers provide immediate volume but break down completely. Biostimulators stimulate collagen production – the result develops more slowly but lasts longer and looks more natural.
For Sculptra, 2-3 sessions at 4-6 week intervals are usually optimal. HArmonyCa can often deliver sufficient results in 1-2 sessions.
Yes, combining with Botox, fillers, or skin boosters is possible and often beneficial for a comprehensive anti-aging approach.
Swelling, redness, and tenderness are normal and subside within a few days. With Sculptra, small nodules may occur, which are treated with massage.
Biostimulators are particularly suitable from 40+, when the body's own collagen production significantly decreases. For younger patients, other treatments are often more appropriate.
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
Ready for Your Personal Consultation?
Schedule a consultation now and find out which treatment is best for you. Consultation €50 – credited if treated the same day.