Bio-Regeneration
Polynucleotides in Karlsruhe
Innovative bio-regeneration for your skin
Medically reviewed by the Derma Luma medical team · Last updated: October 2026
Polynucleotides – The Future of Skin Regeneration
Polynucleotides (PDRN) are an innovative treatment method for deep skin regeneration. At Derma Luma in Karlsruhe, we use this advanced technology to repair and rejuvenate your skin at the cellular level.
Treatment Areas
Applications
Polynucleotides (PDRN) are highly pure DNA fragments derived from salmon roe. They work at the cellular level and stimulate tissue regeneration.
PDRN activate fibroblasts and promote the production of collagen, elastin, and the body's own hyaluronic acid.
Polynucleotides are also successfully used to treat hair loss by regenerating the scalp and promoting hair growth.
Suitability
Who is this treatment suitable for?
✓ Suitable for
- •Damaged or tired skin
- •Sun-damaged skin
- •Scars and acne scars
- •Hair loss and thinning hair
- •Sensitive or reactive skin
- •After aggressive treatments for regeneration
✗ Less suitable for
- •Allergy to fish or fish protein
- •Pregnancy and breastfeeding
- •Acute skin infections
Process
How the treatment works
1
Skin analysis: Assessment of skin condition and regeneration needs
2
Preparation: Cleansing and gentle numbing if needed
3
Injection: Precise injections into the treated areas
4
Regeneration phase: Care recommendations for optimal healing
Investment
Prices & Costs
Polynucleotides facefrom €299
Polynucleotides scalpfrom €299
Polynucleotides eye areafrom €299
3-session course (recommended)from €699
Safety
Risks & Safety
✓Highly pure, biocompatible products
✓Clinically tested and approved
✓Natural origin
✓No synthetic additives
✓Experienced application
Durability & Aftercare
The regenerative effects build up over the treatment series and last approximately 6-12 months after completion. The improvement in skin quality is often long-lasting. Refresher treatments 1-2 times per year optimize the results.
FAQ
Frequently Asked Questions
While skinboosters primarily provide hydration, polynucleotides work regeneratively at the cellular level. They are particularly suitable for damaged skin and for deep repair processes.
People with allergies to fish or fish protein should be cautious, as PDRN is derived from salmon roe. We clarify possible allergies during the consultation.
For optimal results, we recommend a series of 3-4 treatments at 2-4 week intervals. Afterwards, refresher treatments can maintain the results.
Yes, polynucleotides are successfully used to treat hair loss and promote hair growth by regenerating the scalp.
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- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
- GaldermaSculptra · Restylane
- AllerganJuvéderm · HArmonyCa™
- IBSAProfhilo
- MedSanLipolyse
- Nordberg MedicalJULÄINE™ of Sweden
- Merz Aesthetics®Radiesse®
- FillmedNCTF
Ready for Your Personal Consultation?
Schedule a consultation now and find out which treatment is best for you. Consultation €50 – credited if treated the same day.